Immunology
This is a series of lectures stressing basic concepts in immunology. They include: development of the immune system, innate versus acquired immunity, immunoglobulin structure and genetics, antigen-antibody reactions, the major histocompatibility complex and antigen presentation, T cell receptors (Genetics, structure, selection), T cell activation and effector functions, cytokines, B cell activation and effector functions, anergy and apoptosis, adhesion molecules, phagocytic cell function, immune responses to infectious organisms and tumors, autoimmune diseases, immune deficiencies and AIDS. (Term 2, Every Year)
Session |
TOPIC |
Faculty |
1 |
Overview | Rodgers |
2 |
Ig and TCR structure/genetics | Zheng |
3 |
Ig and TCR structure/genetics | Zheng |
4 |
Innate Immune Mechanisms | Corry |
5 |
Major histocompatibility genes and proteins | Cook |
6 |
Antigen processing and presentation | Cook |
7 |
Immune receptor signaling | Chen/Tan |
8 |
Measurements of Lymphocytes/T cell selection | Lewis/Spencer |
9 |
T cell selection | Spencer |
10 |
T cell effector functions | Lewis |
11 |
Memory cell development; Regulatory T cells | Lewis |
| EXAM I | ||
12 |
Signaling in apoptosis/anergy | Chen/Tan |
13 |
Cytokine receptors/signaling | Corry |
14 |
B cell activation/differentiation | Han |
15 |
B cell effector function | Han |
16 |
Adhesion molecules and migration | Rodgers |
17 |
Phagocytic cell function | Rossen |
18 |
Host response against infectious organisms; Mucosal Immunity | Rossen |
19 |
Tissue injury and autoimmune disease | Corry |
20 |
Immune response to tumors & transplanted tissue | Spencer |
21 |
Immunodeficiencies and AIDS | Lewis |
| FINAL EXAM |