Ervin Adam, M.D. Ph.D.
Role of Viruses in Neoplasia
- Professor
Ph.D.-Charles University Medical School, Prague, CZECH Republic
M.D.-Medicine, Charles University Medical School, Prague, CZECH Republic
713-798-4446- eadam@bcm.edu
Herpesviruses. The association of herpes simplex virus (HSV) types 1 and 2 with female genital neoplasia has been studied for many years, and a serum and tissue bank has been established in the laboratory. Well-documented samples provide a means to study new methods for the detection of virus-associated antigens and antibodies in clinical specimens. Human papillomaviruses (HPV) have been directly implicated as potential causative agents for carcinoma of the lower genital tract of women. The presence of HPV and HSV genomes and of viral specific antigens is being traced in neoplastic tissue specimens.
1:Daxnerova Z, Berkova Z, Kaufman RH, Adam E.Detection of human cytomegalovirus DNA in 986 women studied for human papillomavirus-associated cervical neoplasia. J Low Genit Tract Dis. 2003 Jul;7(3):187-93.PMID: 17051067 [PubMed - in process]
2:Berkova Z, Kaufmann RH, Unger ER, Reeves WC, Adam E.The effect of time interval between referral and colposcopy on detection of human papillomavirus DNA and on outcome of biopsy. Am J Obstet Gynecol. 2003 Apr;188(4):932-7.PMID: 12712088
3: Butel JS, Wong C, Vilchez RA, Szücs G, Dömök I, Kríz B, Slonim D, Adam E.Detection of antibodies to polyomavirus SV40 in two central European countries.Cent Eur J Public Health. 2003 Mar;11(1):3-8.PMID: 12690795
4:sKaufman RH, Adam E.Findings in female offspring of women expos in utero to diethylstilbestrol Obstet Gynecol. 2002 Feb;99(2):197-200.PMID: 11814496
5: Kaufman RH, Adam E, Hatch EE, Noller K, Herbst AL, Palmer JR, Hoover RN.Continued follow-up of pregnancy outcomes in diethylstilbestrol-exposed offspring.Obstet Gynecol. 2000 Oct;96(4):483-9.PMID: 11004345
6: Kaufman RH, Adam E, Vonka V.Human papillomavirus infection and cervical carcinoma.Clin Obstet Gynecol. 2000 Jun;43(2):363-80. Review. No abstract available. PMID: 10863634
7: Moniak CW, Kutzner S, Adam E, Harden J, Kaufman RH.Endocervical curettage in evaluating abnormal cervical cytology.J Reprod Med. 2000 Apr;45(4):285-92.PMID: 10804483