Clinical Research
The following are research studies conducted by individual investigators.
- Dr. Malcolm K. Brenner
Activity of Lymphotactin in Childhood Malignancy.
Treatment of Hodgkin's Disease with Gene Marked cytotoxic T lymphocytes.
Cytotoxic T Cell Transfer for Therapy of EBV Lymphoma.
Effects of CD45 Monoclonal Antibodies on Normal and Malignant Hemopoiesis.
Therapeutic Effects of CD 40L in Acute Lymphoblastic Leukemia. - Dr. Paul Bray
Study of coronary artery bypass graft patients taking aspirin to identify platelet assays and genotypes that predict aspirin failure.
Study of patients with myocardial infarction before the age of 45 years to identify new platelet risk factors.
Correlating platelet polymorphisms with platelet hyperreactivity in healthy subjects.
Effects of hormone replacement therapy on platelet function.Research contact: Anu Dave 713-798-1482
For clinic appointment: 713-394-3800 - Dr. Powel H. Brown
Molecular basis of breast cancer prevention. - Dr. George Carrum
Pilot study of allogeneic stem cell transplantation with sub-myeloablative conditioning therapy for hematological diseases.
High dose chemotherapy for Stage II/III breast cancer without stem cell rescue. - Dr. Jenny Chang
Locally advanced breast cancer.
Neoadjuvant chemotherapy.
Predictive and prognostic markers in breast cancer. - Dr. Richard Elledge
Biomarkers as surrogate endpoints in a pilot breast cancer chemoprevention trial using tamoxifen.
A multi-center, randomized, double-blind study of Idoxifene 40 mg/day versus Tamoxifen 20 mg/day as first-line hormonal therapy of locally advanced or metastatic breast cancer in postmenopausal women.
A multicenter phase III randomized, controlled study of Theratope vaccine for metastatic breast cancer, SWOG 9319.
Tumor characteristics and clinical outcome of tubular and mucinous breast carcinomas.
Evolutionary changes of molecular markers in response to neoadjuvant doxorubicin for locally advanced breast cancer.
For clinic appointments: 713-798-1999 - Dr. Daniel Epner
Phase I clinical trial of methionine-restricted diet for patients with refractory solid tumors. - Dr. Terry Hayes
Selenium and Vitamin E Prostate Cancer Prevention Trial (SELECT).
Diet and Lifestyle Factors in Early Stage Prostate Cancer.
Phase I/II safety and dose escalation study of therapy with recombinant human lactoferrin (rhlf) in patients with metastatic cancer.
L-selenium-based chemoprevention of prostate cancer among men with high grade prostatic intraepithelial neoplasia (High Grade PIN).
Research nurse: Dori Smith 713-791-1414, ext. 5313 - Dr. Helen Heslop
Immunotherapy with EBV specific CTLs for EBV-positive Hodgkin's Disease.
Immunotherapy with EBV specific CTLs for nasopharyngeal cancer.
Immunotherapy with EBV specific CTLs for PTLD.
Augmenting antiviral and anti-tumor immunity after hemopoietic stem cell transplants.
Clinical research nurses for Dr. Heslop:
Goley Richardson 713-441-1038
Susan Feliciano 713-394-6942 - Dr. Michael Kroll
AIDS-related malignancies. - Dr. G. Rushing Lynch
Incidence of HIV Infection in Cancer Patients at an Urban Teaching Hospital. - Dr. C. Kent Osborne
Biology, diagnosis, prognostic factors, prevention and treatment of breast cancer.
For clinic appointments: 713-798-1999 - Dr. Uday Popat
High dose therapy for autoimmune diseases.
Immune ablation and allogeneic stem cell therapy for solid tumors. - Dr. Josef Prchal
Polycythemia vera.
Myeloproliferative diseases.
Contact information for Myeloproliferative Disease Clinic:
Diann Whisennand 713-793-8996 - Dr. Heidi Weiss
Biostatistical methods for the design and analysis of preclinical and clinical trials in cancer chemoprevention.
Prognostic studies of biomarkers using survival analysis.
Longitudinal analysis of tumor multiplicity in animal chemoprevention studies.
Surveillance and epidemiology of cancer incidence and mortality.