References
Here are some very good references that explain some of the issues involved with cDNA microarray data analysis. These papers give researchers a good idea into what to expect from microarray data as well as a basic overivew of how microarray data is processed.
- Design Issues For cDNA Microarray Experiments.
Yang YH, Speed T.
Nature Reviews Genetics 2002 Aug; 3 (8): 579-588
Nature Reviews - Genetics - Normalization for cDNA microarray data: a robust composite method addresssing single and multiple slide systematic variation.
Yang YH, et al
Nucleic Acids Research 2002 Feb 15; 30 (4): e15
Nucleic Acids Research - Computational analysis of microarray data.
Quackenbush J.
Nat Rev Genet 2001 Jun; 2 (6): 418-27
Nature Reviews - Genetics - Gene expression profile analysis by DNA microarrays: promise and pitfalls.
King HC, Sinha AA.
JAMA 2001 Nov 14; 286 (18): 2280-8
JAMA - Microarrays: handling the deluge of data and extracting reliable information.
Hess KR, Zhang W, Baggerly KA, Stivers DN, Coombes KR, Zhang W.
Trends Biotechnol 2001 Nov; 19 (11): 463-8
Trends in Biotechnology - Issues in cDNA microarray analysis: quality filtering, channel normalization, models of variations and assessment of gene effects.
Tseng GC, Oh MK, Rohlin L, Liao JC, Wong WH.
Nucleic Acids Res 2001 Jun 15 ; 29 (12): 2549-57
Nucleic Acids Research - Expression Profiling - Best Practices for Data Generation and Interpretation in Clinical Trials
The Tumor Analysis Working Group. Contact: Hoffman, Eric P.
Nature Reviews Genetics 2004 March; 5 (3): 229-236
Nature Reviews - Genetics