Publications
Liu, X. and Davis, R.L. (2008). The GABAergic anterior paired lateral neuron of Drosophila suppresses and is suppressed by olfactory learning. Nat. Neurosci. (EPub ahead of print). Abstract
Tomchik, S.M. and Davis, R.L. (2008). Behavioural neuroscience: Out of sight, but not out of mind. Nature 453, 1192-1194. Abstract
Tomchik, S.M. and Davis, R.L. (2008). Cyclic AMP imaging sheds light on PDF signaling in circadian clock neurons. Neuron 58, 161-163. Abstract
Berry, J., Krause, W., Davis, R.L. Olfactory memory traces in Drosophila. In Progress n Brain Research: The Essence of Memory Vol 169. Eds. W. Sossin, J.C. Lacaille, V.F. Castellucci and S. Belleville. Elsevier B.V. (Oxford). 2008. Abstract
Nicholson, L., Kaur, G., Roman, G.W., Davis, R.L., and Keshishian, H. (2008). Spatial and temporal control of gene expression using the inducible gene-switch Gal4 system: L screen for larval nervous system drivers. Genetics 178, 215-34. Abstract
Liu, X., Krause, W.C., and Davis, R.L. (2007). GABAA receptor RDL inhibits Drosophila olfactory associative learning. Neuron, 56, 1090-102. Abstract
Chan, C.S., Levenson, J.M., Mukhopadhyay, P.S., Zong, L., Bradley, A., Sweatt, J.D., and Davis, R.L. (2007). α3-integrins are required for hippocampal long-term potentiation and working memory. Learning & Memory 14, 606-615. Abstract
Davis, R.L. (2007). The scent of Drosophila sex. Neuron 54, 14-16. Abstract
Liu, L., Davis, R.L., and Roman, G. (2007). Exploratory activity in Drosophila requires the Drosophila non-visual arrestin. Genetics 175, 1-16. Abstract
Urizar, N. L., Yang, Z., Edenberg, H. J. and Davis, R. L. (2007). Drosophila Homer is required in a small set of neurons including the ellipsoid body for normal ethanol sensitivity and tolerance. J. Neurosci., 27, 4541-4551. Abstract
Liu, X., and Davis, R.L. (2006). Insect olfactory memory in time and space. Curr. Opin. Neurobiol. 6, 679-685. Abstract
Ge, H., Krishnan, P., Liu, L., Krishnan, B., Davis, R.L., Hardin, P.E., and Roman, G. (2006). A Drosophila nonvisual arrestin is required for the maintenance of olfactory sensitivity. Chem. Senses 31, 49-62. Abstract
Yu, D., Akalal, D.-B., and Davis, R. L. (2006). Drosophila α/β mushroom body neurons form a branch-specific, long-term cellular memory trace after spaced olfactory conditioning. Neuron 52, 845-855. Abstract
Chan, C.S., Weeber, E.J., Zong, L., Fuchs, E., Sweat, J.D., and Davis, R.L. (2006). β1-Integrins are required for hippocampal AMPA receptor-dependent synaptic transmission, synaptic plasticity, and working memory. J. Neurosci. 26, 223-233. Abstract
Akalal, D-B. G., Wilson, C., Zong, L., and Davis, R.L. (2006). Roles for Drosophila mushroom body neurons in olfactory learning. Learning & Memory, 13, 659-668. Abstract
Yang, Z., Edenberg, H., and Davis, R. L. (2005). Isolation of mRNA from specific tissues of Drosophila by mRNA tagging. Nucleic Acid Res. 33, e148. Absract
Davis, R. L. (2005). Olfactory memory formation in Drosophila: From molecular to systems neuroscience. Ann. Rev. Neurosci. 28, 275-302. Abstract
McGuire, S.E., Deshazer, M., and Davis, R.L. (2006). 30 years of olfactory learning and memory research in Drosophila melanogaster. Progress in Neurobiology, 76, 328-347. Abstract
Yu, D., Keene A.C., Srivatsan, A., Waddell, S., and Davis, R.L. (2005). Drosophila DPM neurons form a delayed and branch-specific memory trace after olfactory classical conditioning. Cell 123, 945-957. Abstract
Martini, S. R. and Davis, R. L. (2005). The dachshund gene is required for the proper guidance and branching of mushroom body axons in Drosophila melanogaster. J. Neurobiol. 64, 133-44. Abstract
Davis, R. L. (2005). Remote control of fruit fly behavior. Cell, 121: 6-7. Abstract
Davis, R.L. (2004). Olfactory learning. Neuron 44, 31-48. Abstract
Perazzonza, B., Isabel, G., Preat, T., and Davis, R.L. (2004). The role of CREB in Drosophila long-term memory. J. Neurosci. 24, 8823-8828. Abstract
McGuire, S. E., Roman, G., and Davis, R. L. (2004). Gene expression systems in Drosophila: A synthesis of time and space. Trends in Genetics 20, 384-391. Abstract
Yu, D., Ponomarev, A. and Davis, R.L. (2004). Altered representation of the spatial code for odors after olfactory classical conditioning: memory trace formation by synaptic recruitment. Neuron 42, 437-449. Abstract
McGuire, S.E., Mao, Z., Davis, R.L. (2004). Spatiotemporal gene expression targeting with the TARGET and gene-switch systems in Drosophila. Science STKE 2004(220), l6. Abstract
McGuire, S.E., Le, P.T., Osborn, A.J., Matsumoto, K., and Davis, R.L. (2003). Spatio-temporal Rescue of Memory Dysfunction in Drosophila. Science 302, 1765-1768.
*[Article highlighted by Wang Y and Zhong Y. (2004). TARGETing "when" and "where". Science STKE. 2004, pe5. and Waddell, S. (2004). Four dimensional gene expression control: Memories on the fly. Trends in Neurosciences, in press.] Abstract
Mao, Z., Roman, G., Zong, L., and Davis, R. L. (2004). Pharmacogenetic rescue in time and space of the rutabaga memory impairment using Gene-Switch. Proc. Natl. Acad. Sci. USA, 101,198-203. Abstract
Lee, H.-G., Seong, C.-S., Kim, Y.-C., Davis, R. L. and Han, K.-A. (2003). Octopamine receptor OAMB is required for ovulation in Drosophila melanogaster. Develop. Biol., 264, 179-190. Abstract
Ponomarev, A. L. and Davis, R. L. (2003). An adjustable-threshold algorithm for the identification of objects in three dimensional images. Bioinformatics,19,1431-1435. Abstract
Chan, C.-S., Weeber, E. J., Kurup, S., Sun, H., Sweatt, J. D. and Davis, R. L. (2003). Integrin requirement for hippocampal synaptic plasticity and spatial memory. J. Neurosci., 23(18), 7107-7116. Abstract
Nishihara, E., Yoshida-Komiya, H., Chan, C.-S., Liao, L., Davis, R. L., Xu, J., and O’Malley, B. W. (2003). SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar purkinje cells. J. Neurosci. 23, 213-222. Abstract
Yu, D., Baird, G. S., Tsien, R. Y., and Davis, R. L. (2003). Detection of calcium transients in Drosophila mushroom body neurons with camgaroo reporters, J. Neurosci. 23, 64-72. Abstract
Roman, G. and Davis, R. L. (2002). Conditional expression of UAS-transgenes in the adult eye with a new gene-switch vector system. Genesis 34, 127-131. Abstract
McGuire, S. and Davis, R. L. (2001). Presenilin-1 and memories of the forebrain. Neuron 32, 763-765. Abstract
Roman, G., Endo, K, Zong, L, and Davis, R.L. (2001). P{Switch}, a novel system for spatial and temporal control of gene expression in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 98, 12602-12607. Abstract
McGuire, S.E., Le, P.T., and Davis, R.L. (2001). The role of Drosophila mushroom body signaling in olfactory memory. Science 10, 1126-1129.
*[Article highlighted by Waddell, S., and Quinn, W.G. (2001). Neurobiology. Learning how a fruit fly forgets. Science 293, 1271-1272]. Abstract
Davis, R.L. (2001). Mushroom bodies, Ca2+ oscillations, and the memory gene amnesiac. Neuron 30, 653-656. Abstract
Cheng, Y., Endo, K., Wu, K., Rodan, A.R., and Davis, R.L. (2001). Drosophila fasciclinII is required for the formation of odor memories for normal sensitivity to alcohol. Cell 105, 757-768.
*[Article highlighted by Waddell, S., and Quinn, W.G. (2001). Fas-Acting Memory. Developmental Cell 1, 8-9]. Abstract
Roman, G. and Davis, R.L. (2001). Molecular biology and anatomy of Drosophila olfactory associative learning. BioEssays 23, 1-11. Abstract
Davis, R.L. (2001). Genetics of memory in the fly. In "International Encyclopedia of the Social & Behavioral Sciences," (N. Smelser and P. Baltes, eds.), Elsevier Science Limited (Oxford).
Rohrbough, J., Grotewiel M.S., Davis, R.L., and Broadie, K. (2000). Integrin-mediated regulation of synaptic morphology, transmission, and plasticity. J. Neurosci. 20, 6868-6878. Abstract
Roman, G., He, J., and Davis, R.L. (2000). Kurtz, a novel non-visual arrestin, is an essential neural gene in Drosophila. Genetics 155, 1281-1295. Abstract
Martini, S.R., Roman, G., Meuser, S., Mardon G., and Davis, R.L. (2000). The retinal determination gene, dachshund, is required for mushroom body cell differentiation. Development 127, 2663-2672. Abstract
Davis, R.L. (2000). Neurofibromin progress in the fly. Nature News & Views 403, 846-847. Abstract
Beck, C.D.O., Schroeder, B., and Davis, R.L. (2000). Learning performance of Drosophila after repeated conditioning trials with discrete stimuli. J. Neurosci. 20, 2944-2953. Abstract
Zars, T., Reinhard W., and Davis, R., and Heisenberg, M. (2000). Tissue specific expression of a type I adenylyl cyclase in the rutabaga mutant rescues its memory defect: In search of the engram. Learning & Memory 7, 18-31. Abstract
Kelley, R. L, Meller, V.H., Gordadze, P.R., Roman, G., Davis, R.L., and Kuroda, M.I. (1999). Epigenetic spreading the Drosophila dosage compensation complex from roX RNA genes into flanking chromatin. Cell 98, 513-522. Abstract
Farris, S.M., Robinson G.E., Davis, R.L, Fahrback, S.E. (1999). Larval and pupal development of the mushroom bodies in the honey bee, Apis mellifera. J. Comp. Neuro. 414, 97-113. Abstract
Roman, G., He, J., and Davis, R.L. (1999). New series of Drosophila expression vectors suitable for behavioral rescue. BioTechiques 27, 54-56. Abstract
Cherry, J.A. and Davis, R.L. (1999). Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect. J. Comp. Neuro. 407, 287-301. Abstract
Roman, G., Meller, V., Wu, K.-H. and Davis, R.L. (1998). The opt1 gene of Drosophila melanogaster encodes a proton dependent dipeptide transporter. Am. J. Physiol. 275, C857-C869. Abstract
Crittenden, J., Skoulakis, E. M. C., Han, K.-A., Kalderon, D. and Davis, R. L. (1998). Tripartite mushroom body architecture revealed by antigenic markers. Learning & Memory 5, 38-51. Abstract
Skoulakis, E.M.C. and Davis, R. L. (1998). 14-3-3 proteins in neuronal development and function. Mole. Neurobiol. 16, 269-284. Abstract
Delgado, R., Davis, R. L., Bono, M. R., Latorre, R., and Labarca, P. (1998). Outward currents in Drosophila larval neurons: dunce lacks a maintained outward current component down regulated by cyclic AMP. J. Neurosci. 18, 1399-1407. Abstract
Grotewiel, M.S., Beck, C.D.O., Wu, K.-H., Zhu, X.-R. and Davis, R.L. (1998). Integrin-mediated short-term memory in Drosophila. Nature 391, 455-460.
*[Article highlighted by: Bargmann, C. (1998). Molecular neurobiology. Making memories stick? Nature 391, 435-436 and Connolly, J.B., and Tully, T. (1998). Integrins: a role for adhesion molecules in olfactory memory. Curr. Biol. 8, R386-R389]. Abstract
Han, K.-A., Millar, N. S., and Davis, R. L. (1998). A novel octopamine receptor with preferential expression in Drosophila mushroom bodies. J. Neurosci. 18, 3650-3658. Abstract
Li, W., Skoulakis, E.M.C., Davis, R. L., and Perrimon, N. (1997). The Drosophila 14-3-3 protein Leonardo enhances Torso signaling through D-Raf in a Ras1-dependent manner. Development 124, 4163-4171. Abstract
Broadie, K., Rushton, E., Skoulakis, E.M.C. and Davis, R. L. (1997). Leonardo, a Drosophila 14-3-3 protein involved in learning, regulates presynaptic function. Neuron 19, 391-402. Abstract
Meller, V. H., Wu, K.-H., Roman, G., Kuroda, M. and Davis, R. L. (1997). roX1 RNA paints the X chromosome of male Drosophila and is regulated by the dosage compensation system. Cell 88, 445-457.
*[Article highlighted by Willard, H.F, and Salz, H.K. (1997). Remodeling chromatin with RNA. Nature 386, 228-229]. Abstract
Skoulakis, E.M.C. and Davis, R. L. (1996). Olfactory learning deficits in mutants for Leonardo, a Drosophila gene encoding a 14-3-3 protein. Neuron 17, 931-944. Abstract
Han, K.-A., Millar, N. S., Groteweil, M. S., and Davis, R. L. (1996). DAMB, a novel dopamine receptor expressed specifically in Drosophila mushroom bodies. Neuron 16, 1127-1135. Abstract
Davis, R. L. and Han, K.- A. (1996). Mushrooming mushroom bodies. Current Biology 6, 146-148. Abstract
Meller, V.H. and Davis, R.L. (1996). Biochemistry of insect learning: lessons from bees and flies. Insect Biochem. & Mole. Biol. 26, 327-335. Abstract
Davis, R. L. (1996). Biochemistry and physiology of Drosophila learning mutants. Physiol. Reviews 76, 299-317. Abstract
Han, P.-L., Meller, V.H. and Davis, R. L. (1996). The Drosophila brain revisited by enhancer detection. J. Neurobiol. 31, 88-102. Abstract
Davis, R. L., Cherry, J.A., Dauwalder, B., Han, P.-L. and Skoulakis, E. M.C. (1995). The cyclic AMP system and Drosophila learning. J. Mole. & Cell. Biochem. 149/150, 271-278. Abstract
Cherry, J. A. and Davis, R. L. (1995). A mouse homolog of dunce, a gene important for learning and memory in Drosophila, is preferentially expressed in olfactory receptor neurons. J. Neurobiol. 28, 102-113. Abstract
Dauwalder, B. and Davis, R. L. (1995). Conditional rescue of the dunce learning/memory and female fertility defects with Drosophila or rat transgenes. J. Neurosci. 15, 3490-3499. Abstract
Nighorn, A., Qiu, Y. and Davis, R. L. (1994). Progress in understanding the Drosophila dnc locus. Comp. Biochem. & Physiol., 108B, 1-9. Abstract
Skoulakis, E.M.C., Han, P.-L. and Davis, R.L. (1993). Learning and memory in Drosophila. In "Memory Concepts: Basic and Clinical Aspects," (P. Anderson, A. Bjorkland, B. Hokfelt and T. Hokfelt, eds.), Novo Nordisk Foundation Symposium No. 7, Elsevier Science Publishers, (Amsterdam), pp. 99-112.
Davis, R. L. (1993). Mushroom bodies and Drosophila learning. Neuron 11, 1-4. Abstract
Skoulakis, E., Kalderon, D. and Davis, R. L. (1993). Preferential expression of the catalytic subunit of PKA in the mushroom bodies and its role in learning and memory. Neuron 11, 197-208. Abstract
Qiu, Y. and Davis, R. L. (1993). Genetic dissection of the learning/memory gene dunce of Drosophila melanogaster. Genes & Develop. 7, 1447-1458. Abstract
Han, P.-L., Levin, L., Reed, R.R. and Davis, R.L. (1992). Preferred expression of the Drosophila rutabaga gene in mushroom bodies, neural centers for learning in insects. Neuron 9, 619-627. Abstract
Levin, L., Han, P.-L., Hwang, P.M., Feinstein, P.G., Davis, R.L. and Reed, R.R. (1992). The Drosophila learning and memory gene rutabaga encodes a Ca2+/calmodulin-responsive adenylyl cyclase. Cell 68, 479-489. Abstract
Qiu, Y., Chen, C.-N., Malone, T., Richter-Mann, L., Beckendorf, S. and Davis, R.L. (1991). Characterization of the memory gene dunce of Drosophila melanogaster. J. Mole. Biol. 222, 553-565. Abstract
Davis, R.L. and Dauwalder, B. (1991). The Drosophila dunce locus and its mammalian homologs. Trends in Genetics 7, 224-229. Abstract
Nighorn, A., Healy, M. and Davis, R.L. (1991). The cAMP phosphodiesterase encoded by the Drosophila dunce gene is concentrated in mushroom body neuropil. Neuron 6, 455-467. Abstract
Davis, R.L. (1990). Molecular genetics of the cyclic nucleotide phosphodiesterases. In "Cyclic Nucleotide Phosphodiesterases: Structure, Regulation and Drug Action," (J. Beavo and M. Houslay, eds.), John Wiley and Sons Limited (Chichester), pp. 227-241.
Livi, G.P., Kmetz, P., McHale, M.M., Cieslinski, L.B., Sathe, G.M., Taylor, D.P., Davis, R.L., Torphy, T.J. and Balcarek, J.M. (1990). Cloning and expression of cDNA for a human low-Km, rolipram-sensitive cyclic AMP phosphodiesterase. Mole. Cell. Biol. 10, 2678-2686. Abstract
Davis, R.L., Henkel-Tigges, J., Qiu, Y. and Nighorn, A. (1990). Phosphodiesterase genes from flies to mammals. In "Purines in Cellular Signaling: Targets for New Drugs," (K. Jacobson, J. Daly, and V. Manganiello, eds.), Springer-Verlag (New York), pp. 290-296.
Pittler, S.J., Baehr, W., Wasmuth, J., Champagne, M., van Tuinen, P., Ledbetter, D. and Davis, R.L. (1990). Molecular characterization of human and bovine rod photoreceptor cGMP phosphodiesterase a-subunit and chromosomal localization of the human gene. Genomics 6, 272-283. Abstract
Henkel-Tigges, J. and Davis, R.L. (1990). Rat homologs of the Drosophila dunce gene code for cyclic AMP phosphodiesterases sensitive to the antidepressant rolipram. Mole. Pharm. 37, 7-10. Abstract
Yun, Y. and Davis, R.L. (1989). Copia RNA levels are elevated in dunce mutants and modulated by cAMP. Nucl. Acids Res. 17, 8313-8325. Abstract
Davis, R.L., Takayasu, H., Eberwine, M. and Myres, J. (1989). Cloning and characterization of mammalian homologs of the Drosophila dunce+ gene. Proc. Natl. Acad. Sci. USA 86, 3604-3608. Abstract
Yun, Y. and Davis, R.L. (1989). Levels of RNA from a family of putative serine protease genes are reduced in Drosophila melanogaster dunce mutants and are regulated by cyclic AMP. Mole. Cell. Biol. 9, 692-700. Abstract
Davis, R.L. (1989) Ribonucleic acid (RNA). In "The 1989 McGraw-Hill Yearbook of Science & Technology," (S.P. Parker, ed.) McGraw-Hill Book Company (New York) pp. 218-220.
Davis, R.L. (1988). Mutational analysis of the Drosophila phosphodiesterases. In "Methods in Enzymology," Vol. 159 (J. Corbin and R. Johnson, eds.), Academic Press (San Diego), pp. 786-792. Abstract
Chen, C.-N., Malone, T., Beckendorf, S. and Davis, R.L. (1987). At least two genes reside within a large intron of the Drosophila dunce gene. Nature 329, 721-724. Abstract
Pittler, S. and Davis, R.L. (1987) A new family of the class of polydeoxyadenylated transposable elements identified by a representative member inserted into the dunce+ locus. Mole. Gen. Genetics 208:325-328. Abstract
Pittler, S., Salz, H. and Davis, R.L. (1987). An interchromosomal gene conversion of the Drosophila dunce locus identified with restriction site polymorphisms: A potential involvement of transposable elements in gene conversion. Mole. Gen. Genetics 208, 315-324. Abstract
Chen, C.-N., Denome, S. and Davis, R.L. (1986). Molecular analysis of cDNA clones and the corresponding genomic coding sequences of the Drosophila dunce+ gene, the structural gene for cAMP phosphodiesterase. Proc. Natl. Acad. Sci. USA 83, 9313-9317. Abstract
Davis, R.L. and Davidson, N. (1986). The memory gene dunce+ encodes a remarkable set of RNAs with internal heterogeneity. Mole. Cell. Biol. 6, 1464-1470. Abstract
Davis, R.L. and Kauvar, L.M. (1984). Drosophila cyclic nucleotide phosphodiesterases. In "Advances in Cyclic Nucleotide Research," Vol. 16 (S. Strada and W. Thompson, eds.), Raven Press (New York), pp. 393-402. Abstract
Davis, R.L. and Davidson, N. (1984) Isolation of the Drosophila melanogaster dunce+ chromosomal region and recombinational mapping of dunce sequences with restriction site polymorphisms as genetic markers. Mole. Cell. Biol. 4, 358-367. Abstract
Salz, H., Davis, R.L. and Kiger, J.A., Jr. (1982). Genetic analysis of chromomere 3D4: The dunce and sperm-amotile genes of Drosophila melanogaster. Genetics 100, 587-596.
Kiger, J.A., Jr., Davis, R.L., Salz, H., Fletcher, T. and Bowling, M. (1981). Genetic analysis of cyclic nucleotide phosphodiesterases in Drosophila melanogaster. In "Advances in Cyclic Nucleotide Research," Vol. 14 (J.E. Dumont, P. Greengard and G. Alan Robison, eds.), Raven Press (New York). Abstract
Davis, R.L. and Kiger, J.A., Jr. (1981). The dunce mutants of Drosophila melanogaster: Mutants defective in the cyclic AMP phosphodiesterase enzyme system. J. Cell Biol. 90, 101-107. Abstract
Byers, D., Davis, R.L. and Kiger, J.A., Jr. (1981). Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster. Nature 289:79-81. Abstract
Davis, R.L. and Kiger, J.A., Jr. (1980). Biochemical characterization of the cyclic nucleotide phosphodiesterases of Drosophila melanogaster. Arch. Biochem. Biophys. 203, 412-421. Abstract
Davis, R.L. and Kiger, J.A., Jr. (1978). Genetic manipulation of cyclic AMP levels in Drosophila melanogaster. Biochem. Biophys. Res. Comm. 81, 1180-1186. Abstract
Davis, R.L. and Kiger, J.A., Jr. (1977). A clonal analysis of tergite development in Drosophila of ultraabdominal and paradoxical genotypes. Dev. Biol. 58, 114-123. Abstract