Research Interests
The following is a list of some of our current research interests:
- MHC structure and function
- Biology of Germinal Center reactions and mechanisms of normal and pathologic B cell immune responses.
- Signal transduction mechanisms of lymphocyte activation and apoptosis
- Signaling pathways and caspase signaling cascades
- Somatic genetics and development of immune responses; immunosenescence; autoimmunity
- Genetic control of immune responses
- Inflammation in response to cardiac injury
- Mechanisms of allergic responses in the lung
- Novel approaches to vaccine development
- Immune responses to gene therapy
- Activation of Ig Genes and B-cells by HIV-1 gp120
- Mechanisms of HIV Pathogenesis
- Protein Chemistry Core Laboratory offers peptide synthesis, protein identification and characterization by mass spectrometry and sequencing, and MHC class I tetramer production.
- Faculty Research
- T32 Fellowship Support NIAID - Tse-Hua Tan, Ph.D., (PI)