Lab Publications
Neuronal Development
J.Visvayatan, S.Lee, B.Lee, J.W.Lee, and S.K.Lee. The microRNA miR-124 antagonizes the antineural REST/SCP1-pathway during embryonic CNS development. Genes Dev 21: 744-9, 2007
S.Lee, B.Lee, K.Joshi, S.L.Pfaff, J.W.Lee, and S.K.Lee. A novel regulatory network to segregate spinal neuronal identities. Dev Cell 14: 877-89, 2008
K.Joshi, S.Lee, B.Lee, J.W.Lee, and S.K.Lee. LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons. Neuron 61:839-851, 2009
S.Lee, B.Lee, J.W.Lee, and S.K.Lee. Retinoid signaling and Ngn2 function are coupled for the specification of spinal motor neurons through a chromatin modifier CBP. Neuron 62:641-654, 2009
S.Lee and S.K.Lee. Epigenetic control of neurogenesis. Curr Opin Neurobiol (invited review)
Transcription and Metabolism
S.-K.Lee and J.W.Lee. Mammalian two-hybrid assay for detecting protein-protein interactions in vivo. Methods Mol Biol 261: 327-336, 2004 (book chapter)
Y.H.Goo, S.-Y.Na, H.Zhang, J.Xu, S.Hong, J.Cheong, S.K.Lee, J.W.Lee. Interactions between activating signal cointegrator-2 and the tumor suppressor retinoblastoma in androgen receptor transactivation. J Biol Chem 279: 7131-7135, 2004
S.Lee, D.Lee, Y.Dou, J.Lee, B.Lee, E.Kwak, Y.Kong, S.K.Lee, R.G..Roeder, and J.W.Lee. A coactivator as a target gene specificity determinant for histone H3-lysine 4 methyltransferases. Proc Natl Acad Sci USA 103: 15392-7, 2006
S.Lee, J.Lee, S.K.Lee, and J.W.Lee. Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors. Mol Endocrinol 22:1312-9, 2008
J.Lee, P.K.Saha, Q.H.Yang, S.Lee, J.Y.Park, Y.Suh, S.K.Lee, L.Chan, R.G.Roeder, and J.W.Lee. Targeted inactivation of MLL3 histone H3-lysine-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis. Proc Natl Acad Sci USA 105:19229-19234, 2008
S.Lee, D.H.Kim, Y.H.Goo, Y.C.Lee, S.K.Lee, and J.W.Lee. Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation. Mol Endocrinol 23: 610-619, 2009
J.Lee, D.H.Kim, S.Lee, Q.H.Yang, D.K.Lee, S.K.Lee, R.G.Roeder, and J.W.Lee. Characterization of a tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4. Proc Natl Acad Sci USA, in press, 2009