Xiao-Tong Song, Ph.D.

Instructor Department of Immunology Center for Cell and Gene Therapy Baylor College of Medicine

Contact Information:
xsong1@bcm.tmc.edu
xxtongso@txccc.org
832-824-3305

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Education:
Ph.D., Nanjing Medical University, Nanjing, China
Post-doctoral fellow, Baylor College of Medicine, Houston, TX

Research Interests:
Dr. Song's research interests include vaccine development for viral and malignant diseases and adoptive immunotherapy for solid tumors with genetically modified T lymphocytes.

Selected Publications:
Song XT, Evel-Kabler K, Rollins L, Aldrich M, Huang XF, Chen SY. A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell-mediated suppression of antitumor immunity. Nature Medicine 2008 Mar 02; 14(3): 258-265.

Song XT, Aldrich M, Chen SY. SOCS1 inhibition strategy to enhance anti-HIV vaccination. Expert Review of Vaccines. 2006 Aug; 5(4):495-503.

Song XT, Evel-Kabler K, Rollins L, Aldrich M, Gao F, Huang XF, Chen SY. An Alternative and Effective HIV Vaccination Approach Based on Inhibition of Antigen Presentation Attenuators in Dendritic Cells. PLoS, Medicine. 2006 Jan 3; 3(1):e11.

Evel-Kabler K, Song XT, Aldrich M, Huang XF, Chen SY. SOCS1 restricts dendritic cells’ ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling. Journal of Clinical Investigation. 2006 Jan; 116(1 ):90-1 00.

Planque S, Bangale Y, Song XT, Karle S, Taguchi H, Poindexter B, Bick R, Edmundson A, Nishiyama Y, Paul S. Ontogeny of proteolytic immunity: IgM serine proteases. Journal of Biological Chemistry. 2004 Apr 2;279(14):14024-32.

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(Modified:August 15, 2006- SM)