Contact Information:
xfu@bcm.tmc.edu
713-798-1250

---

Education:
MD - Hubei Medical College , Huanggang , Hubei , China
Surgery for Master of Medicine - Tongji Medical University , Hubei , China

Research Interests:

Selected Publications:

Delivery of herpes simplex virus vectors through liposome formulation. Mol Ther. 2001, 4:447.

Isomerization of a uniquely designed amplican during herpes simplex virus-mediated replication. J Virol. 2001,75:10505.

Potent systemic antitumor activity from an oncolytic herpes simplex virus of syncytial phenotype. Can Res. 2002, 62:2306.

High frequency of intermolecular homologous recombination during HSV- mediated plasmid replication. J Virol. 2002, 76:5866.

Expression of a fusogenic membrane glycoprotein by an oncolytic herpes simplex virus potentiates the viral antitumor effect. Mol Ther. 2003,7:748

Effective Therapy of metastatic ovarian cancer with an oncolytic herpes simplex virus incorporating two membrane-fusion mechanisms. Clin Can Res. 2003, 9: 2727.

A strict-late viral promoter is a strong tumor-specific promoter in the context of an oncolytic herpes simplex virus. Gene Ther. 2003, 10:1458.

Destruction of nonimmunogenic mammary tumor cells by a fusogenic oncolytic herpes simplex virus induces potent antitumor immunity. Mol Ther 2004, 9:658

Potent antitumor activity after systemic delivery of a doubly fusogenic oncolytic herpessimplex virus. Gene Ther. 2003, 10:1458.

Potent antitumor activity after systemic delivery of a doubly fusogenic oncolytic herpes simplex virus against metastatic prostate cancer. Prostate. 2004 Jun 15; 60:53-60.