Cell and Gene Therapy Program

Program Projections

Optimizing the therapeutic potential of cell and gene therapy requires a fundamental understanding of the molecular pathophysiology of disease as well as expertise in gene transduction (transfer) techniques, vector development, stem cell biology, cellular immunology, and stem cell transplantation. Baylor College of Medicine has made a significant long-term commitment to further enhance the basic research areas related to cell and gene therapy, including the identification of genes, gene expression and regulation, target cell identification, development of animal models of disease, and vector development and large scale production.

The development of comprehensive adult and pediatric Cell and Gene Therapy Transplant units at The Methodist Hospital and Texas Children’s Hospital will lead to the expansion of the therapeutic applications for stem cell transplantation, and will facilitate the translation of laboratory breakthroughs into clinical cell and gene therapies. These innovative units will provide the capability for performing all types of stem cell transplantation, cellular therapy, and gene therapy, as well as provide seamless care for the patient by providing inpatient, outpatient, and infusion areas within the same unit. These units will also provide the environment for the implementation of clinical research studies in gene therapy, transplantation involving novel conditioning regimens, and the potential role of transplantation as novel therapy for diseases such as systemic lupus erythematosis, rheumatoid arthritis, and multiple sclerosis. Included in the comprehensive program plan is the Cell and Gene Therapy Protocol office which will facilitate the preparation of protocols for FDA approval and compliance for novel cell and gene therapy studies, as well as provide the resources for data management.

The Cell and Gene Therapy program provides an exciting opportunity for all three institutions and will be unique to the Texas Medical Center and Houston. This program will attract patients throughout the United States and around the world. With the support of Baylor College of Medicine, The Methodist Hospital, and Texas Children’s Hospital, the program will be instrumental in developing and providing innovative cellular and gene therapies in a cost-effective and affordable manner.

©2002, Cell And Gene Therapy, Baylor College of Medicine
One Baylor Plaza, N1002, Houston, TX 77030, (713)798-1246
URL: http://www.bcm.edu/genetherapy Email:cagt@bcm.edu
(Modified: September 21st, 2007 - jb)