Hemophagocytic Disease


H8713; Phase I/II Study of Allogeneic Stem Cell Transplantation for Patients with Hematologic Malignancy, Using Haploidentical Family Donors and Sub-Myeloablative Conditioning with Campath 1H: This study uses a monoclonal antibody, low dose chemotherapy and radiation combined with haploidentical allogeneic stem cell transplantation to treat patients with hematologic malignancies who have already received a stem cell transplant or who also have other complications such as kidney, liver, or heart disease.

H21580: A Phase I Study Evaluating the use of Allodepleted T Cells Transduced with Inducible Caspase 9 Suicide Gene After Haploidentical Stem Cell Transplantation:   This study is an add on study in which patients who have received a haploidentical stem cell transplant are eligible to receive allodepleted T cells following engraftment.  The T-cells may help the immune system recover so that the body can fight infections.

 

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(Modified: September 21st, 2007 - jb)