Studies - Substance Abuse
Laboratory Models of Cocaine Self Administration (H-23131)
We are currently looking for people who use cocaine and smoke cigarettes for our two-phase, 10 day inpatient- inpatient research study. The purpose of this study is to find out if disulfiram, also known as antabuse, can reduce cocaine use and determine safety and effects of disulfiram when used together with cocaine. You will receive either placebo or cocaine and a limited amount of cocaine or placebo, IV. You will have to answer questions about your personal and family psychiatric history, including alcohol and drug abuse. You will be compensated for participating. If you are seeking treatment, you should not participate in this study and the investigators can refer you to organizations that offer treatment for cocaine addiction.
Contact: If interested, please call 877-228-5777 for more information. All calls will be confidential.
Rivastigmine as a Treatment for Methamphetamine Dependence (H-23064)
The purpose of this study is to determine whether Rivastigmine, a potential treatment for methamphetamine abuse, is safe when used together with methamphetamine. If participants qualify for the study, they will be hospitalized for 27 days total on a research unit at Michael DeBakey VA Medical Center. Participants will receive either Rivastigmine or placebo for 12 days during the study. They will also receive a small dose of injected methamphetamine on 12 days during the study. After receiving the study drugs, participants' blood pressure and heart rate will be measured, and they will be asked to answer questions about how they feel. Participants will be compensated. If you are seeking treatment, you should not participate in this study and the investigators can refer you to organizations that offer treatment for methamphetamine addiction.
Contact: If interested, please call 877-228-5777 for more information. All calls will be confidential.