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Cain Foundation Core Laboratories


The Cain Foundation supports the operation of several core laboratories that are located within the Cain Foundation Laboratories in the Feigin Center. The core labs provide resources that are shared by all Cain investigators. At the present time, there are four core laboratories.

Molecular Biology Core
This laboratory supports a wide range of projects in the Cain Laboratories. Equipment includes:

Packard 2500 Beta Scintillation Counter
Beckman Coulter Optima LE-80K Ultracentrifuge
Sorvall RC-5B Refrigerated Superspeed Centrifuge
Sorvall RC-35 Refrigerated Centrifuge
INNOVA 4400 Incubator Shaker (2)

Tissue Culture Core
Two laboratories are available for studies of neuron in culture. One core laboratory is devoted to primary cultures of neurons from the developing brain, the second is used to study cell lines. Equipment in these labs include:

Tissue Culture Lab 1

2 Sterilgard Biohazard Hood
2 Forma Scientific Incubators
Tissue Culture Lab 2

2 Biogard Biohazard Hoods
1 Steri-cult 200 Incubator

Confocal Microscopy Core
This core laboratory provides facilities for Cain investigators to use state-of-the-art confocal microscopy to image nervous tissue. These facilities also allow the study of nerve cell growth and trafficking of molecules in living neurons. Equipment includes:

Olympus BX5OWIF Microscope
Flowview Confocal Scanning System
Argon, Krypton, Helium Neon Lasers
Software for image processing and analysis

Gene Microarray Core
This core laboratory, managed by Mr. John Le, is responsible for manufacturing custom gene microarrays for Cain investigators. Equipment includes:

Storm 860 Scanner, Computer and Image Analysis Software
S/S Microsample Filtration Manifolds
Hybaid Thermocycler
Hybaid Hybridization Ovens
Beckman Coulter Allegra Centrifuge
Napco Vacuum Oven



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(c)1998-2006 Baylor College of Medicine
Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories
   Feigin Center, Suite 955, Texas Children's Hospital
1102 Bates Avenue, MC 3-6365
Houston, TX 77030
Phone: 832-824-3968 | Fax: 832-825-4217
E-mail: Cain_Found@bcm.tmc.edu

Last Modified: September 17, 2009