Florante A. Quiocho, Ph.D.
Charles C. Bell Professor, Structural Biology
Professor, Dept. of Biochemistry & Molecular Biology
Professor, Dept. of Molecular Physiology & Biophysics
Education
- Ph.D., Biochemistry, 1966, Yale University
Structural Biophysics and Biology: X-Ray Crystallography of Proteins
Three-dimensional structures of biological macromolecules lie at the very core of understanding, at the atomic level, biological and biochemical processes. Our research interest is centered on the study of the three-dimensional structure and function of proteins and enzymes at atomic resolution. Although x-ray crystallography is the primary experimental approach to achieve this goal, other correlative studies employing biochemical, physical-chemical, and recombinant DNA techniques are also being pursued. The proteins under investigation cover the areas of signal transduction and cellular regulation, active transport, ligand and drug molecular recognition and vesicular trafficking and membrane fusion.
